Invertebrate Immunology and Nanosafety

Group Leader
Annalisa Pinsino


Institute of Translational Pharmacology (IFT)
National Research Council (CNR)
Via Ugo La Malfa 153, 90146 Palermo, Italy.

Membri del Laboratorio

Giovanna Montana,
Mauro Biondo,
Iacopo Sorrentino


Nanotoxicology- Ecological immunology- Comparative immunology- Innate immunity- Cell Biology – Developmental Biology- Molecular Biology- Proxy for human models- Environmental Risk

Experience in molecular and cellular studies, with a focus on cell regulation, signaling, and differentiation mechanisms influencing development, life maintenance, and immune response.

Current research focuses on the understanding of the biosafety of nanoparticles in an emergent proxy for a human non-mammalian model for in vitro basic and translational immunology: the sea urchin Paracentrotus lividus.

Progetti principali e partners

PANDORA- EU H2020 research and innovation program under the Marie Skłodowska-Curie grant agreement [No 671881] (subproject: In vitro short-term cultures of sea urchin immune cells: characterization of the innate/inflammatory responses to NP). Consortium Member: CNR-IBBC, CNR-IRIB; PLUS; UNIGE; IMIC; EKUT; UNILJ; CU; NERC; ACS; AN.

Eco-SUN- Ecodesign of Sunscreen Using titanium dioxide Nanoparticles- Labex Serenade funding. Task 3.4: Impact on the sea urchin biological model. Consortium Member: CEREGE/CNRS; UJF/Isterre; CEA/LEMIRE; INERIS/Ardevie; CEA/LITEN; Novancia Business School; INRA/BIA; EPHE/CNRS/UPVD/CRIOBE, CNR/IRIB, COSMED; COSMEBIO.

NanoScreen- DOC2AMU doctoral programme, EU H2020 research and innovation program under the Marie Skłodowska-Curie grant agreement [No 713750]. Consortium Member: CEREGE/CNRS; Institut Fresnel; CNR-IRIB; Industrial Companies

Strumenti / Tecnologie

Dedicated animal maintenance room, Invertebrate Cell Culture incubator, particle manipulation place, TransBlot SD Semi-Dry Western Transfer Apparatus, LiCor Odyssey technology, Real-Time PCR machine, microscopes. Etc.

Altre informazioni

Joint lab with the Lab of Metabolomics (Institute of Molecular Bioimaging and Physiology, Milan, IBFM-CNR, Head: Daniela Gaglio) and the Lab of Innate Immunity, Inflammation and Nanosafety (Institute of Biochemistry and Cell Biology, Naple, IBCC-CNR, Head: Paola Italiani)