DNA Vaccine Technology
Membri del Laboratorio
Daniela Fioretti (ricercatore CNR T.D.)
Sandra Iurescia (ricercatore CNR T.D.)
Alice Mecchia (laureanda Dip.to Biologia Uni Tor Vergata)
Anti-idiotypic DNA Vaccination in B-cells Lymphoma Preclinic protocols of genetic immunization against tumor-associated antigens Combination therapy: (vaccination+immunotherapy+chemotherapy) DNA vaccine and biotechnology; Targeted therapy: antigen-specific therapy, polyepitope vaccines; Adjuvant therapy; Cancer immunotherapy; Cancer vaccines; Immunological response.
Strumenti / Tecnologie
Development of innovative vaccine formulations for anticancer therapy and/or prevention, intended for clinical application: multigenic plasmid vectors; set-up of in vivo electroporation technology; DNA vaccine immunomodulatory adjuvants; electroporation and prime-boost protocols Naked in vivo gene transfer