DNA Vaccine Technology

Group Leader
Monica Rinaldi

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Istituto

Membri

Attività

Strumenti / tecnologie

Istituto

Istituto di Farmacologia Traslazionale
ARoma, Via Fosso del Cavaliere 100, 00133
Tel. +39 06 49934219
http://www.ift.cnr.it/

Membri del Laboratorio

Daniela Fioretti (ricercatore CNR T.D.)

Sandra Iurescia (ricercatore CNR T.D.)

Alice Mecchia (laureanda Dip.to Biologia Uni Tor Vergata)

Attività

Anti-idiotypic DNA Vaccination in B-cells Lymphoma Preclinic protocols of genetic immunization against tumor-associated antigens Combination therapy: (vaccination+immunotherapy+chemotherapy) DNA vaccine and biotechnology; Targeted therapy: antigen-specific therapy, polyepitope vaccines; Adjuvant therapy;
Cancer immunotherapy; Cancer vaccines; Immunological response.

Strumenti / Tecnologie

Development of innovative vaccine formulations for anticancer therapy and/or prevention, intended for clinical application: multigenic plasmid vectors; set-up of in vivo electroporation technology; DNA vaccine immunomodulatory adjuvants; electroporation and prime-boost protocols Naked in vivo gene transfer

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