The CNR Immunology Network was established in 2016 with the aim of

  • Strengthening the interaction and cooperation
  • Fostering and spreading scientific information
  • Enhancing visibility and impact of the CNR immunological research
  • Creating international networks to enhance new funding opportunities 

Immunologists from 18 Institutes of the National Research Council of Italy are CIN associate and  they belong to 5 Departments (Biomedical Sciences; Biology, agriculture and food sciences; Chemical sciences and materials technology; Engineering, ICT and technologies for energy and transportation). The memberships have a long-standing interest in cell and molecular immunology approaches dealing with the immune system in health and disease.




Our activities are run in the following Research Areas :

Infection, innate immunity, and inflammation

The research includes the study of innate immune cell signaling, immunomodulatory mechanisms and functions, immunotoxicity, cytokines, innate immune cell biology through advanced imaging technologies, molecular biology, and omics approaches. Moreover, we are focused on the role of the innate immune system in chronic inflammatory diseases, allergy ...

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Adaptive Immunity

We aim at deciphering the mechanisms underlying the role of T and B lymphocytes in adaptive immune responses as well as to the interactions between the adaptive immune system and different tissues during disease pathogenesis to attempt novel therapeutic approaches. Intracellular signaling mechanisms regulating T cell development, differentiation, induction...

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Immunogenetics and immune-related diseases

Our main goal is to identify specific targets and pathways for informing the design of more specific treatments for autoimmune disorders. Through association studies (GWAS) on immunological traits quantified in the general population, we seek to identify genetic variants to evaluate their role in the predisposition to autoimmune diseases, characterize ...

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Immuno-therapeutic approaches

Our aims are the formulation of innovative vaccines (against infectious and not-infectious diseases) and the design of strategies for targeting specific cell subsets using antigen nanocarriers. We design vaccine with free and/or NP bound recombinant allergens to modulate allergen specific immune response, and propose Fcγ-chimeric receptor engineered T ...

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Interdisciplinary Collaborations

CIN scientists are actively promoting new partnerships with bioinformatics, mathematicians and physicists within CNR, to increase communication, exchange of ideas, applying complementary tools as an innovative, multidisciplinary approach to studying the immune response and immune related disorders

Computational Immunology

Mathematical modelling for immunology | Network medicine and immunology | Analysis and integration of omics data with application to biomedical research

Immune system-on-chip

Modelling and measuring the IS by a microfluidic based approach


For a knowledge-based growth and innovation

CIN is committed to improving public understanding of immunology and promoting health protection by an active engagement in communication to the general audience.

CIN is active in organizing webinars on key topics : 

 Thursday, April 15th, 2021

 Alessandro Sette

 Comprehensive analysis of adaptive immune   responses   to SARS-CoV-2

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 Thursday, May 4th, 2021

 Mihai G. Netea

Trained immunity: a memory for innate host defense

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 Thursday, May 18th, 2021

 Rita Carsetti

 Different B cell immunity to   SARS-CoV- 2 after   infection  and vaccination

 registration link

 Thursday, June 15th, 2021

 Rudolf Valenta

 From molecular immunotherapy of allergy towards prophylactic allergy vaccination

 registration link

 Thursday, July 1st, 2021

 Oreste Acuto

 How does T-cell activation begin?

 registration link

 July, 13th, 2021

 Josef Penninger

 ACE2 – from discovery to the heart of a pandemic

 registration link

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