The CNR Immunology Network was established in 2016 with the aim of
- Strengthening the interaction and cooperation
- Fostering and spreading scientific information
- Enhancing visibility and impact of the CNR immunological research
- Creating international networks to enhance new funding opportunities
Immunologists from 18 Institutes of the National Research Council of Italy are CIN associate and they belong to 5 Departments (Biomedical Sciences; Biology, agriculture and food sciences; Chemical sciences and materials technology; Engineering, ICT and technologies for energy and transportation). The memberships have a long-standing interest in cell and molecular immunology approaches dealing with the immune system in health and disease.
Infection, innate immunity, and inflammation
The research includes the study of innate immune cell signaling, immunomodulatory mechanisms and functions, immunotoxicity, cytokines, innate immune cell biology through advanced imaging technologies, molecular biology, and omics approaches. Moreover, we are focused on the role of the innate immune system in chronic inflammatory diseases, allergy ...
read moreAdaptive Immunity
We aim at deciphering the mechanisms underlying the role of T and B lymphocytes in adaptive immune responses as well as to the interactions between the adaptive immune system and different tissues during disease pathogenesis to attempt novel therapeutic approaches. Intracellular signaling mechanisms regulating T cell development, differentiation, induction...
read moreImmunogenetics and immune-related diseases
Our main goal is to identify specific targets and pathways for informing the design of more specific treatments for autoimmune disorders. Through association studies (GWAS) on immunological traits quantified in the general population, we seek to identify genetic variants to evaluate their role in the predisposition to autoimmune diseases, characterize ...
read moreImmuno-therapeutic approaches
Our aims are the formulation of innovative vaccines (against infectious and not-infectious diseases) and the design of strategies for targeting specific cell subsets using antigen nanocarriers. We design vaccine with free and/or NP bound recombinant allergens to modulate allergen specific immune response, and propose Fcγ-chimeric receptor engineered T ...
read moreInterdisciplinary Collaboration
Computational Immunology
Mathematical modelling for immunology | Network medicine and immunology | Analysis and integration of omics data with application to biomedical research
Immune system-on-chip
Modelling and measuring the IS by a microfluidic based approach
ImmunoNutrition
Functional foods and metabolic stress prevention
Dissemination
Immunology for school
