The CNR Immunology Network was established in 2016 with the aim of
Immunologists from 18 Institutes of the National Research Council of Italy are CIN associate and they belong to 5 Departments (Biomedical Sciences; Biology, agriculture and food sciences; Chemical sciences and materials technology; Engineering, ICT and technologies for energy and transportation). The memberships have a long-standing interest in cell and molecular immunology approaches dealing with the immune system in health and disease.
The research includes the study of innate immune cell signaling, immunomodulatory mechanisms and functions, immunotoxicity, cytokines, innate immune cell biology through advanced imaging technologies, molecular biology, and omics approaches. Moreover, we are focused on the role of the innate immune system in chronic inflammatory diseases, allergy ...
read moreWe aim at deciphering the mechanisms underlying the role of T and B lymphocytes in adaptive immune responses as well as to the interactions between the adaptive immune system and different tissues during disease pathogenesis to attempt novel therapeutic approaches. Intracellular signaling mechanisms regulating T cell development, differentiation, induction...
read moreOur main goal is to identify specific targets and pathways for informing the design of more specific treatments for autoimmune disorders. Through association studies (GWAS) on immunological traits quantified in the general population, we seek to identify genetic variants to evaluate their role in the predisposition to autoimmune diseases, characterize ...
read moreOur aims are the formulation of innovative vaccines (against infectious and not-infectious diseases) and the design of strategies for targeting specific cell subsets using antigen nanocarriers. We design vaccine with free and/or NP bound recombinant allergens to modulate allergen specific immune response, and propose Fcγ-chimeric receptor engineered T ...
read moreCIN scientists are actively promoting new partnerships with bioinformatics, mathematicians and physicists within CNR, to increase communication, exchange of ideas, applying complementary tools as an innovative, multidisciplinary approach to studying the immune response and immune related disorders
Mathematical modelling for immunology | Network medicine and immunology | Analysis and integration of omics data with application to biomedical research
Modelling and measuring the IS by a microfluidic based approach
CIN is committed to improving public understanding of immunology and promoting health protection by an active engagement in communication to the general audience.
CIN is active in organizing webinars on key topics :
Thursday, April 15th, 2021
Alessandro Sette
Comprehensive analysis of adaptive immune responses to SARS-CoV-2
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Thursday, May 4th, 2021
Mihai G. Netea
Trained immunity: a memory for innate host defense
review webinar
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Thursday, May 18th, 2021
Rita Carsetti
Different B cell immunity to SARS-CoV- 2 after infection and vaccination
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Thursday, June 15th, 2021
Rudolf Valenta
From molecular immunotherapy of allergy towards prophylactic allergy vaccination
July, 13th, 2021
Josef Penninger
ACE2 – from fly hearts to the heart of a pandemic
Prof. Penninger’s group generated the first ACE2 mutant mice which they initially identified studying fly heart development. They then developed ICUs for lung failure in mice which allowed us to …
https://www.mdpi.com/journal/ijms/special_issues/Autoimmunity_Nervous
