Innate Immunity, Inflammation and Nanosafety
Group Leaders

Diana Boraschi
- +39-081-6132314 (office)
- +39-081-6132367 (lab)
- diana.boraschi@ibbc.cnr.it
- Sito web istituzionale

Paola Italiani
- +39-081-6132314 (office)
- +39-081-6132367 (lab)
- paola.italiani@ibbc.cnr.it
- Sito web istituzionale
Istituto
Istituto di Biochimica e Biologia Cellulare
Via Pietro Castellino 111 , 80131 Napoli
Tel. 0816132273
http://www.ibbc.cnr.it
Membri del Laboratorio
Annunziata Corteggio (ricercatore) annunziata.corteggio@ibbc.cnr.it
Daniela Melillo (assegno senior) daniela.melillo@ibbc.cnr.it
Giacomo Della Camera (dottorando) giacomo.dellacamera@ibbc.cnr.it
Ana Margarida Campos (dottorando) margarida.campos@ibbc.cnr.it
Nguyen The Phuc 8 (assegnista) thephuc.nguyen@ibbc.cnr.it
Rita Marino (tecnologo associato da Stazione Zoologica “Anton Dohrn”)
Attività
- Mechanisms of activation and polarisation of human monocytes and macrophage-derived macrophages
- Mechanisms of induction and modulation of innate memory of monocytes and macrophages
- Role of inflammatory cytokines in chronic inflammatory, immune-related and degenerative diseases
- Biology of IL-1 family cytokines
- Immunosafety of engineered nanoparticles, with focus on innate immunity, inflammation, and innate memory.
- Evaluation of innate memory induction and modulation in the marine invertebrate Ciona intestinalis
- In vitro tissue-like 3D models for studying human macrophage functions.
Principali progetti e partners
Partners
- Lab with the Lab of Invertebrate Immunology and Nanosafety (Institute for Biomedical Research and Innovation – IRIB-CNR, Head: Dr Annalisa Pinsino)
- Joint Lab with the Lab of Evolution of Immune System (Institute of Biochemistry and Cell Biology – IBBC-CNR, Head: Dr Maria Rosaria Coscia)
- University of Salzburg
- University of Pisa
- University of Catania
- Catalan Institute of nanoscience and nanotechnology
- Stazione Zoologica “Anton Dohrn”
- • European Commission, Joint Research Centre, Ispra (IT)
Progetti
- PRIN 2017 “NanoTechVax Tackling biological barriers to antigen delivery by nanotechnological vaccines”. Prot. 20173ZECCM.
- H2020 ETN project “ENDONANO: Quantitative detection of bacterial ENDOtoxin by novel NANOtechnological approaches”. H2020-MSCA-ITN-2018 – EID- 812661.
- PNRA 2018 “Impact of the Antarctic environments on human homeostasis, psychology, physiology and immunology”
- PNRA 2016 “Effects of extreme environments on psychophysiology, energy metabolism and immunity: neuropsychological, immunohistochemical, proteomic and fMRI studies”
Strumenti / Tecnologie
- Cell isolation and culture
- Gene expression (real-time PCR)
- Functional & immunochemical assays
- FACS facility
- Imaging facility (confocal, live imaging, correlative microscopy, electron microscopy
- MS facility for proteins, small molecules, lipids and glycans



