Classical and non-classical HLA, immunogenetics of transplantation and diseases (celiac, Alzheimer disease); population genetics
Group Leader
Daniela Piancatelli
- +39-0862-318843
- daniela.piancatelli@cnr.it
- Sito web istituzionale
Istituto
Istituto di Farmacologia Traslazionale,
Via Carducci 32, 6710 – L’ Aquila
http://www.ift.cnr.it/
Membri del Laboratorio
Anna Aureli anna.aureli@cnr.it
Angelica Canossi angelica.canossi@cnr.it
Daniela Piancatelli daniela.piancatelli@cnr.it
HLA polymorphism in transplantation and diseases. Polymorphisms of non classical HLA and HLA-related loci. Tolerance and immune disregulation in kidney transplantation. Role of Fc γ receptor and KIR/HLA in cancer and degenerative diseases. Cytokines in diseases. Immunogenetics of Alzheimer disease and developmental neurological disorders. Characterization of novel alleles. Population genetics; immunogenetics of celiac disease.
CIN website:
D. Piancatelli – Classical and non-classical HLA, immunogenetics of transplantation and diseases (celiac, Alzheimer disease); population genetics.
A. Aureli – Fc receptors, CD1 and BDNF in cancer and diseases.
A. Canossi – Immunogenetics of Treg biomarkers in organ transplantation (CTLA4, FOXP3); KIR/HLA in cancer and immune-related diseases.
Principali progetti e collaborazioni
DSB.AD007.043 “Marcatori biomolecolari e genetici in patologie immunologiche e neurodegenerative”.
Strumenti / Tecnologie
Sequence-based typing, genotyping/allelic discrimination, gene expression (RT-PCR), cell cultures, ELISA.