Immunology and Inflammation

Group Leader
Elena Lo Presti

Istituto

Istituto per la Ricerca e l’Innovazione Biomedica

Via Ugo La Malfa, 153 – 90146 Palermo
Tel. +39 0503757523
https://www.irib.cnr.it/

Attività

  • Tumor immunology: evaluation of percentage, phenotype and function of pancreatic cancer and colorectal cancer infiltrating lymphocytes and their correlation with DFS, stage and disease recurrence to find new immunotherapeutic approaches.
  • Chronic inflammation: evaluation of the role of innate immune system in the pathogenesis of IBD with particular attention to the non-responder patients to current biological therapies.

Partners

Partners:

  • Policlinico Hospital “P.Giaccone” di Palermo and BIND at University of Palermo
  • -ARNAS Civico di Palermo

Strumenti / Tecnologie

Flow cytometry, sorting, Glomax, RT-PCR, Luminex, immunological assays (cytotoxicity, proliferation assay, cytokines expression, primary cell lines from PBMC, extraction of infiltrating lymphocytes from cancer and healthy tissues), cell transfection.