Group Leader
Silvia D’Amico
- +39 06 4993 4715 / 3388294339
- Silvia.damico@cnr.it
- Sito web istituzionale
Istituto
Istituto di Farmacologia Traslazionale
Via Fosso del Cavaliere 100 – 00133 Roma
Tel. +39 06 45488486
http://www.ift.cnr.it
Attività
- Dissection of tumor immune heterogeneity and crosstalk between tumor and immune cells.
- Development of new strategies for local modulation of the tumor immune microenvironment and enhancement of tumor immunogenicity.
- Development of combination therapies to extend the area of efficacy of current immunotherapeutic approaches.
Strumenti / Tecnologie
- Cell isolation and culture
- CRISPR/Cas9 gene editing
- Gene expression (real-time PCR)
- Protein expression
- Establishment of mouse and/or patient-derived organotypic tumor spheroids
- Multicolor flow cytometry for tumor microenvironment dissection
- In vitro tumor-immune interaction studies (evaluation of activation status, migration, effector function, proliferation)